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The Most Famous Investigations in FBI History

The Most Famous Investigations in FBI History

Rosenberg Espionage

National Archives and Records Administration, Public domain, via Wikimedia Commons

Black Dahlia murder

Public Domain / Wikimedia Commons

D.B. Cooper hijacking

Public Domain / Wikimedia Commons

Murder of Special Agent Edwin C. Shanahan

Courtesy of the FBI

Bombing of United flight

Public Domain / Wikimedia Commons

Frank Sinatra, Jr., kidnapping

Public Domain / Wikimedia Commons

Reservation murders

Public Domain / Wikimedia Commons

Army deserters kill FBI agent

Courtesy of the FBI

Greenlease kidnapping

Courtesy of FBI

JFK assassination

Wikimedia Commons / Public Domain

Weyerhaeuser kidnapping

Public Domain / Wikimedia Commons

Special Agent J. Brady Murphy slain

Courtesy of the FBI

Krupp diamond theft

Courtesy of the FBI

Special Agent William R. Ramsey murder

Courtesy of the FBI

Judge Vance murder

Joe Raedle / Getty Images

Lindbergh kidnapping

Keystone / Hulton Archive via Getty Images

Robbery spree on East Coast

Public Domain / Wikimedia Commons

Osage murders case

Public Domain / Wikimedia Commons

Unabomber attacks

Stephen J. Dubner / Contributor / Getty Images

Hijacking of United Flight

Public Domain / Wikimedia Commons

Joanne Chesimard terror spree

Public Domain / flickr

Patty Hearst abduction

Public Domain / Wikimedia Commons

German saboteurs

Public Domain / Wikimedia Commons

Robbers in the Midwest

Public Domain / Wikimedia Commons

Rosenberg Espionage
Alcatraz escape
Brinks robbery
Charles Ross kidnapping
Black Dahlia murder
D.B. Cooper hijacking
Murder of Special Agent Edwin C. Shanahan
Bombing of United flight
Frank Sinatra, Jr., kidnapping
Reservation murders
Army deserters kill FBI agent
Greenlease kidnapping
JFK assassination
Weyerhaeuser kidnapping
Special Agent J. Brady Murphy slain
Jonestown mass suicide
Krupp diamond theft
Special Agent William R. Ramsey murder
Judge Vance murder
Lindbergh kidnapping
Robbery spree on East Coast
Osage murders case
Unabomber attacks
Hijacking of United Flight
Murder of Medgar Evers
Joanne Chesimard terror spree
Patty Hearst abduction
Oklahoma City Bombing
German saboteurs
Robbers in the Midwest

Prior to the early 1900s, the United States had no national investigative agency until the establishment of the Federal Bureau of Investigation (FBI). Since its inception, the FBI has been involved in some of the most significant criminal cases in American history.

24/7 compiled a list of the most significant cases in U.S. law-enforcement history, using information sourced from the FBI's website. Our selection process involved editorial judgment, focusing on each case's importance, challenges, historical relevance, and national significance.

According to information from the FBI's website, some of their most consequential cases have included kidnappings, interstate robberies, aircraft hijackings, bombings, murder, and the killing of law enforcement officers. Established in 1908 by Attorney General Charles Bonaparte as a special agent force within the Department of Justice, the FBI was created in response to new national laws like the Espionage Act. Under the leadership of J. Edgar Hoover, who took charge in 1924, the FBI became an important entity in law enforcement.

Throughout the decades, the FBI has handled high-profile cases that received national attention, investigating organized crime, civil rights violations, terrorism, cybercrime, and other significant matters. (Check out 22 notorious unsolved crimes in American history.)

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